Discovering candidate molecules from animal toxins with potential application in biotechnology

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maio 20, 2018
Discovering candidate molecules from animal toxins with potential application in biotechnology

Call for papers in the Journal of Venomous Animals and Toxins including Tropical Diseases.

Edited by Suely V. Sampaio, Eliane C. Arantes and Marco A. Sartim

Envenoming caused by venomous and poisonous animals is considered an important public health threat in tropical countries due to their wide distribution and the high occurrence of accidents in urban and rural areas. This health issue has been encouraging the scientific community to investigate the clinical aspects of envenoming and to search for more effective antivenom therapies. Moreover, the growing concern in discovering novel molecules with potential application as therapeutic agents and/or as biotechnological tools has increased the interest in exploring venoms as natural sources of pharmacologically active compounds. The advances in high throughput approaches in Toxinology, such as the genomic, transcriptomic and proteomic techniques, have unveiled a remarkable functional and structural complexity in venom and poison composition, revealing a variety of molecules that target proteins, receptors, or ion channels with distinct potency and specificity.

Considering the relevance of this issue, the Journal of Venomous Animals and Toxins including Tropical Diseases is calling for papers in a thematic series on “Discovering candidate molecules from animal toxins with potential application in biotechnology”edited by Dr. Suely V. Sampaio, Dr. Eliane C. Arantes and Dr. Marco A. Sartim (University of São Paulo, Brazil). The series will accept research approaching “omics” analysis, structural and biological studies, and biotechnological application comprising venoms and/or isolated toxins from animals.

The submission deadline is July 31, 2018.

Manuscripts should be formatted according to our submission guidelines and submitted via the online submission system. In the submission system, please make sure the correct collection title is chosen from the additional information tab. Please also indicate clearly in the covering letter that the manuscript is to be considered for the “Discovering candidate molecules from animal toxins with potential application in biotechnology” series.

If you would like to enquiry about the suitability of a manuscript for consideration, please email a pre-submission enquiry to editorial@jvat.org.br.

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Research

Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells

Chronic myeloid leukemia (CML) is a BCR-ABL1+ myeloproliferative neoplasm marked by increased myeloproliferation and presence of leukemic cells resistant to apoptosis. The current first-line therapy for CML is ad…

Authors:Rogério Bodini Benati, Tássia Rafaela Costa, Maira da Costa Cacemiro, Suely Vilela Sampaio, Fabíola Attié de Castro and Sandra Mara Burin

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:40

Published on: 20 December 2018

Review

Immunotherapeutic potential of Crotoxin: anti-inflammatory and immunosuppressive properties

For the past 80 years, Crotoxin has become one of the most investigated isolated toxins from snake venoms, partially due to its major role as the main toxic component in the venom of the South American rattles…

Authors:Marco Aurélio Sartim, Danilo Luccas Menaldo and Suely Vilela Sampaio

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:39

Published on: 17 December 2018

Research

Kinetic investigations and stability studies of two Bothrops L-amino acid oxidases

L-amino acid oxidases isolated from snake venoms (SV-LAAOs) are enzymes that have great therapeutic potential and are currently being investigated as tools for developing new strategies to treat various diseas…

Authors:Tássia R. Costa, Sante E. I. Carone, Luiz F. F. Tucci, Danilo L. Menaldo, Nathalia G. Rosa-Garzon, Hamilton Cabral and Suely V. Sampaio

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:37

Published on: 4 December 2018

Research

Deep sequencing analysis of toad Rhinella schneideri skin glands and partial biochemical characterization of its cutaneous secretion

Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein …

Authors:Priscila Yumi Tanaka Shibao, Camila Takeno Cologna, Romualdo Morandi-Filho, Gisele Adriano Wiezel, Patricia Tiemi Fujimura, Carlos Ueira-Vieira and Eliane Candiani Arantes

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:36

Published on: 29 November 2018

Research

Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

Snake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characteriz…

Authors:Rafhaella C. A. Cedro, Danilo L. Menaldo, Tássia R. Costa, Karina F. Zoccal, Marco A. Sartim, Norival A. Santos-Filho, Lúcia H. Faccioli and Suely V. Sampaio

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:33

Published on: 23 November 2018

Research

Purification and enzymatic characterization of a novel metalloprotease from Lachesis muta rhombeata snake venom

Lachesis muta rhombeata (Lmr) is the largest venomous snake in Latin America and its venom contains mainly enzymatic components, such as serine and metalloproteases, L-amino acid oxidase and phospholipases A2. Me…

Authors:Francielle Almeida Cordeiro, Bárbara Marques Coutinho, Gisele Adriano Wiezel, Karla de Castro Figueiredo Bordon, Cristiane Bregge-Silva, Nathalia Gonsales Rosa-Garzon, Hamilton Cabral, Beatrix Ueberheide and Eliane Candiani Arantes

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:32

Published on: 22 November 2018

Research

Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom

In recent decades, snake venom disintegrins have received special attention due to their potential use in anticancer therapy. Disintegrins are small and cysteine-rich proteins present in snake venoms and can i…

Authors:Isadora Sousa de Oliveira, Rafaella Varzoni Manzini, Isabela Gobbo Ferreira, Iara Aimê Cardoso, Karla de Castro Figueiredo Bordon, Ana Rita Thomazela Machado, Lusânia Maria Greggi Antunes, José Cesar Rosa and Eliane Candiani Arantes

Citation:Journal of Venomous Animals and Toxins including Tropical Diseases 2018 24:28

Published on: 20 October 2018

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